时间：2021年11月11日（周四）下午16:00-17:30

Time：16:00-17:30, Thursday, Nov 11, 2021

地点：西湖大学云栖校区5号楼一楼学术报告厅

Venue: Lecture Hall, 1F, Building 5, Yunqi Campus

主持人: 西湖大学理学院PI 石航 博士

Host：Hang Shi, Ph. D., PI of School of Science, Westlake University

雷爱文 教授

武汉大学高等研究院

Prof. Aiwen Lei

College of Chemistry and Molecular Sciences, the Institute for Advanced Studies (IAS), Wuhan University, Wuhan 430072, Hubei, China

主讲人/ Speaker:

Aiwen Lei is Chang Jiang Scholar and currently served as an associate dean of the Institute for Advanced Studies (IAS) of Wuhan University. He has published more than 400 articles with over 22000 citations. His major research interests are in the methodology of oxidative coupling reactions and mechanistic studies including kinetic and active intermediate by using in situ infrared (IR) and X-ray absorption spectroscopy (XAS). In 2019, he received the Yoshida Prize, and 2015 he was granted the Fellow of the Royal Society of Chemistry, FRSC and has won many other awards such as the Roche Chinese Young Investigator Award (2015), Eli Lilly Scientific Excellence Award in Chemistry (2011), CAPA (Chinese-American Chemistry & Chemical Biology Professors Association) Distinguished Faculty Award (2009) etc.

摘要/ Abstract：

Employment of R1-H/R2-H cross coupling has been recognized as powerful and straightforward tool for the construction of C-C/C-X bonds. Over the past decades, significant progress has been made in this field. However, a sacrificial chemical oxidant is always required for the driving force of R1-H/R2-H cross coupling, resulting in a mass of undesired byproducts. A more dream reaction pathway is to achieve oxidative R1-H/R2-H cross-coupling with hydrogen evolution without external oxidants (ΔGrxn>0). Integration of photocatalysis and hydrogen evolution catalysis has emerged as a promising strategy for achieving oxidative coupling with hydrogen evolution (ΔGrxn<0). Electricity has also emerged as a good alternative to chemical oxidant to drive chemical reaction (ΔGrxn<0). Anodic oxidation along with the cathodic proton reduction (H2 evolution) has been widely used in organic synthesis. Compared with classical synthetic methods, these dream transformations feature mild conditions, high atom economy, and elimination of oxidants.

联系人/Contact:

理学院，马倩楠，maqiannan@westlake.edu.cn

School of Science, Qiannan Ma, maqiannan@westlake.edu.cn