时间：2022年8月11日（周四）14:00~15:30

Time：2:00-3:30 PM, Thursday, Aug. 11th, 2022

地点：西湖大学云栖校区3-312

Venue: Room 312, Building 3, Yunqi Campus

主持人：西湖大学生命科学学院讲席教授 于洪涛

Host: Dr. Hongtao Yu, Chair Professor, School of Life Sciences

主讲人/Speaker：

Jijie Chai

University of Cologne, Max Planck Institute for Plant Breeding Research and Tsinghua University 

Jijie Chai completed his PhD study in Peking Union Medical College in 1997, and conducted his postdoctoral research in Princeton University from 1999 to 2004. He joined National Institute Biological Sciences (NIBS) in 2004 to establish an independent laboratory there. After promoted to from an assistance to an associate investigator in 2009, he moved to Tsinghua University. In 2017, he made a second move to join University of Cologne in Germany as an Alexander von Humboldt Professor/W3 Professor.

报告题目/Title:

Biochemical Mechanisms of NLR Signaling in Plants

讲座摘要/Abstract:

Nucleotide binding and leucine-rich repeat (NLR) containing proteins are a large family of intracellular immune receptors conserved in both animals and plants. Plant NLRs mediate specific recognition of pathogen effectors, inducing effector-triggered immunity (ETI). Direct or indirect effector recognition leads to oligomeric assemblies of plant NLRs termed resistosomes that mediate ETI immune signaling. NLR resistosomes can function as calcium-permeable channels or NADase holoenzymes. I will present our studies of resistosomes including their identifications, determination of their biochemical activities, and mechanisms of action. I will also discuss the identification of the catalytic products of resistosome holoenzymes.

讲座联系人/Contact:

科技合作部

sci-tech02@westlake.edu.cn