时间：2023年2月6日（周一）10:30~11:30

Time：10:30-11:30 AM, Monday, Feb. 6, 2023

地点：西湖大学云栖校区 5号楼一楼学术报告厅

Venue: Auditorium, 1F, Building 5, Yunqi Campus

主持人：西湖大学应急医学研究中心 讲席教授孙仁

Host: Chair Professor RenSun, Center for Infectious Disease Research

主讲人/Speaker：

Michael J. Lenardo

Chief, Molecular Development of the Immune System Section

Laboratory of Immune System Biology 

Director, Clinical Genomics Program, NIAID, NIH

报告题目/Title:

New Developments in Genomics for Immune Diseases

讲座摘要/Abstract:

Massively parallel genomic DNA sequencing along with other high-powered molecular technologies have been among the great advances of the 21st century – decreasing in cost by 7 orders of magnitude and opening up new fields of investigation throughout research and clinical medicine. Genomics coupled with biochemical investigation has allowed the molecular definition of a growing number of new genetic diseases that reveal new concepts of immune regulation.

Also, defining the genetic pathogenesis of these diseases has led to improved diagnosis, prognosis, genetic counseling, and, most importantly, new therapies. We highlight the investigational journey from patient phenotype to treatment using the newly defined diseases of the immune system including XMEN, PASLI, CHAI/LATAIE, and CHAPLE disease that show journeys from unknown immunological diseases to new precision medicine treatments using genomics. 

讲座联系人/Contact:

科技合作部 sci-tech02@westlake.edu.cn